Mac and Cheese Meatloaf

Featured in The Stars of the Table.

This innovative comfort food casserole creates remarkable depth by layering perfectly seasoned meatloaf with rich, creamy macaroni and cheese for a satisfying fusion of beloved classics. The meatloaf develops exceptional flavor while the pasta absorbs the creamy cheese sauce, creating distinct yet complementary layers. The make ahead flexibility allows for easy preparation while providing options to customize the cheese blend according to preference. This thoughtful combination transforms two family favorites into an elevated comfort food experience that delivers pure satisfaction.
A smiling woman in a chef's jacket stands in a commercial kitchen, looking at the camera with various food containers and utensils in the background.
Updated on Tue, 14 Jan 2025 22:56:20 GMT
A serving of baked macaroni and cheese layered with ground beef and topped with a golden, crispy crust, garnished with a sprig of parsley. Pin it
A serving of baked macaroni and cheese layered with ground beef and topped with a golden, crispy crust, garnished with a sprig of parsley. | tasteofcook.com

This Mac and Cheese Meatloaf Casserole came to life in my kitchen one cozy Sunday evening when I couldn't decide between making my family's two favorite dishes. The magic happens when velvety mac and cheese meets juicy homestyle meatloaf. Trust me, this combination creates the most comforting dinner you'll ever serve your loved ones.

The Story Behind My Recipe

After years of cooking for potlucks and family gatherings, I discovered that combining these two classics creates something extraordinary. The way the creamy pasta mingles with the savory meatloaf gets me excited every time I make it. My kids actually fight over the crispy cheese corners while my husband always claims the center piece.

What Goes Into My Kitchen Magic

  • Lean Ground Beef: I always pick 85/15 for the perfect balance of flavor and juiciness
  • Ritz Crackers: My secret weapon for the most tender meatloaf you'll ever taste
  • Lipton Onion Soup Mix: This saves so much prep time and adds incredible flavor
  • Macaroni Noodles: The backbone of our creamy pasta layer
  • Cheddar Cheese Soup: Makes the creamiest sauce without any fuss
  • Shredded Mozzarella and Cheddar Cheese: Create that Instagram-worthy cheese pull
  • Ketchup and Barbecue Sauce: The sweet and tangy combo that makes everyone ask for seconds
  • Milk and Seasonings: They bring all the flavors together perfectly

Let's Cook Together

Start With the Meatloaf Base
Mix your beef with crushed Ritz crackers, soup mix, eggs and half of my special sauce blend. Press it into your baking dish and brush the top with remaining sauce.
Give It a Head Start
Pop it in the oven at 350°F for 30 minutes while we work on our mac and cheese layer.
Pasta Time
Cook your macaroni until just tender. I combine it with my signature cheese sauce made from cheddar soup, milk and a generous handful of shredded cheese.
Bringing It All Together
Layer that gorgeous mac and cheese over your meatloaf and sprinkle more cheese on top because why not?
The Final Touch
Back into the oven for about 20 minutes until everything's bubbly and golden. Let it rest a bit before serving.
A close-up of a cheesy, baked macaroni and cheese dish layered with seasoned ground beef. Pin it
A close-up of a cheesy, baked macaroni and cheese dish layered with seasoned ground beef. | tasteofcook.com

My Tried and True Tips

I always weigh my ingredients for consistent results. The pasta should have a little bite when you test it because it'll keep cooking in the oven. Buy blocks of cheese and grate them yourself. The pre-grated stuff just doesn't melt the same way. Give your casserole some time to settle before cutting so you get those perfect squares.

Mix It Up Your Way

  • Different Meats: Ground turkey works beautifully when you want something lighter
  • Veggie Version: My vegetarian friends love it with seasoned lentils instead of meat
  • Cheese Options: Sometimes I splurge on Gruyère when I'm feeling fancy
  • Switch Up the Sauce: Try my honey mustard glaze for a fun twist

Keeping It Fresh

Pop your leftovers in an airtight container and they'll stay good in the fridge for 3 days. I like to freeze individual portions for busy weeknights. They reheat beautifully at 350°F in the oven or you can use the microwave if you're in a hurry.

Complete Your Meal

A simple green salad with vinaigrette cuts through all that delicious richness perfectly. My family loves it with some garlicky roasted broccoli on the side. Sometimes I throw together a quick coleslaw that adds a fresh crunch to every bite.

What Makes This Recipe Special

Every time I serve this casserole it brings back memories of Sunday dinners at my grandmother's house but with my own special twist. The layers look beautiful when you cut into them and that first bite combining the creamy mac with savory meatloaf is pure comfort food heaven.

Share the Love

This recipe has become my go-to dish for neighborhood potlucks and family reunions. It travels well and stays warm forever. I love watching people's faces light up when they taste it for the first time and the way they always come back for more.

A close-up of a baked casserole dish layered with macaroni and cheese and ground beef, garnished with fresh herbs. Pin it
A close-up of a baked casserole dish layered with macaroni and cheese and ground beef, garnished with fresh herbs. | tasteofcook.com

Frequently Asked Questions

→ Can I make this ahead of time?
Yes, assemble the casserole a day ahead and refrigerate. Add extra baking time when cooking from cold to ensure it's heated through.
→ Why use freshly shredded cheese?
Fresh shredded cheese melts better than pre-shredded, which contains anti-caking agents that can affect the texture and melting quality.
→ Can I use different ground meat?
Yes, you can substitute ground turkey or chicken for a lighter version, though the texture and flavor will be slightly different.
→ How should I store leftovers?
Store in an airtight container in the fridge for up to three days, or freeze individual portions for up to three months.
→ What can I serve with this?
Balance the richness with a crisp green salad or steamed vegetables. Garlic bread or crusty bread makes a great accompaniment.

Mac and Cheese Meatloaf

A comforting casserole that combines classic meatloaf with creamy mac and cheese for the ultimate family dinner.

Prep Time
15 Minutes
Cook Time
50 Minutes
Total Time
65 Minutes


Difficulty: Intermediate

Cuisine: American

Yield: 8 Servings (1 casserole)

Dietary: ~

Ingredients

01 1 cup ketchup.
02 1 cup Sweet Baby Ray's Hickory & Brown Sugar barbecue sauce.
03 2 pounds lean ground beef.
04 30 Ritz Crackers, crushed.
05 2 ounces Lipton onion soup mix.
06 2 eggs.
07 3 cups macaroni noodles.
08 2 cups milk.
09 10.5 ounces condensed cheddar cheese soup.
10 1 teaspoon salt.
11 1 teaspoon pepper.
12 1 tablespoon garlic powder.
13 1 tablespoon onion powder.
14 4 cups shredded mozzarella and cheddar cheese blend.

Instructions

Step 01

Preheat oven to 350°F and mix ketchup with barbecue sauce.

Step 02

Combine beef, crackers, onion soup mix, eggs, and half the ketchup mixture. Press into baking dish.

Step 03

Top meatloaf with remaining sauce and bake 30 minutes.

Step 04

Cook macaroni and mix with milk, cheese soup, seasonings, and 2 cups cheese.

Step 05

Spread mac and cheese over meatloaf, top with remaining cheese.

Step 06

Bake additional 17-20 minutes until cheese is melted.

Notes

  1. Can be made ahead and refrigerated.
  2. Fresh shredded cheese works best.
  3. Stores well for freezing.

Tools You'll Need

  • Baking dish.
  • Large pot for pasta.

Allergy Information

Please check ingredients for potential allergens and consult a health professional if in doubt.
  • Dairy.
  • Eggs.
  • Wheat.

Nutrition Facts (Per Serving)

It is important to consider this information as approximate and not to use it as definitive health advice.
  • Calories: 549
  • Total Fat: 28 g
  • Total Carbohydrate: 42 g
  • Protein: 35 g